Say Goodbye To Hair Loss With Ritlecitinib

Say Goodbye To Hair Loss With Ritlecitinib

The FDA approved Pfizer's LITFULO™ (ritelecitinib) for the treatment of adults and adolescents with severe alopecia areata. It is a once-daily oral treatment approved at a recommended dose of 50 mg. This is the first and only FDA-approved treatment for adolescents (ages 12 and older) with severe alopecia areata.

How does Ritlecitinib work?

In people with alopecia areata, the immune system attacks the hair follicles and causes hair growth to slow or stop altogether, leading to hair loss. The active substance in ritlecitinib, is an immunosuppressant (a medicine that reduces the activity of the immune system). It works by blocking the action of certain enzymes called JAK3 and TEC kinases, which play an important role in inflammation. By blocking these enzymes, Ritlecitinib reduces inflammation, allowing hair regrowth in people with alopecia areata.

How is Ritlecitinib taken?

Take this medication by mouth with or without food as directed by your doctor, usually once daily. Swallow the capsules whole. Do not crush, split, or chew the capsules. Use this medication regularly to get the most benefit from it.

For oral dosage form (capsule):

*Adults and children 12 years of age and older—50 milligrams (mg) once a day.

*Children younger than 12 years of age—Use and dose must be determined by your doctor.

How effective is Ritlecitinib for alopecia areata?

In the phase 2b/3 ALLEGRO trial, ritlecitinib was significantly more effective than placebo at improving scalp hair coverage, as measured by the Severity of Alopecia Tool (SALT) score of 20 or less, after 24 weeks in patients aged 12 years and older with alopecia areata and at least 50% scalp hair loss.

What are the most common side effects of Ritlecitinib?

The most common side effects of LITFULO include:

· headache · diarrhea · acne · rash · hives · inflamed hair pores (folliculitis) · fever · eczema · dizziness · shingles · decreased red blood cell counts · mouth sores, redness and swelling of the lining of your mouth

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Pfizer at 1-800-438-1985.

How long will I need to take Ritlecitinib?

The study showed that participants taking ritlecitinib had more hair regrowth on their scalp after 24 weeks than those taking the placebo. Hair regrowth was also seen on the eyebrows and eyelashes in participants taking ritlecitinib. Hair regrowth continued to improve to week 48 with continued ritlecitinib treatment.

How much does Baricitinib cost? Is Baricitinib covered by insurance?

The cost for Litfulo oral capsule 50 mg is around $3,979 for a supply of 28 capsules, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the discount card which is accepted at most U.S. pharmacies.

In general, Medicare prescription drug plans (Part D) do not cover this drug. Be sure to contact your specific plan to verify coverage information.