FDA approves first oral drug to treat Crohn's disease, rheumatoid arthritis

FDA approves first oral drug to treat Crohn's disease, rheumatoid arthritis

The FDA has granted approval for Rinvoq (upadacitinib) for adults diagnosed with moderately to severely active Crohn's disease who have not adequately responded to one or more tumor necrosis factor blockers. Rinvoq marks the first oral medication approved for the treatment of moderately to severely active Crohn's disease.


What is Rinvoq?

Rinvoq, containing the active ingredient upadacitinib, is indicated for the treatment of various inflammatory conditions, including: • Moderately to severely active rheumatoid arthritis • Active psoriatic arthritis • Active ankylosing spondylitis • Active non-radiographic axial spondyloarthritis • Moderate to severe atopic dermatitis • Moderately to severely active ulcerative colitis • Moderately to severely active Crohn's disease

What should I know before I take Rinvoq?

Check the list of ingredients provided at the end of the Consumer Medicine Information (CMI) leaflet. Do not take Rinvoq if you have previously experienced an allergic reaction to any of these ingredients.

Before taking this medication, consult your doctor if you have any other medical conditions, if you are a current or former long-term smoker, if you are taking any other medications, if you are pregnant or planning to become pregnant, or if you are breastfeeding.

What if I am taking other medicines?

Some medications have the potential to interact with Rinvoq, which can impact its effectiveness, or Rinvoq may interact with other medications, affecting their efficacy. It's essential to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements, to prevent any potential interactions. Your doctor can provide guidance on the safe use of Rinvoq in conjunction with other medications.

How do I take Rinvoq?

The typical dosage of Rinvoq is one tablet taken orally once daily. It's important not to split, crush, or chew the tablets. Instead, swallow them whole with a full glass of water, either with or without food.

What should I know while taking Rinvoq?

Things you should do: • Inform any healthcare provider you visit, including doctors, pharmacists, or dentists, that you are taking Rinvoq. • Maintain all scheduled appointments, including blood tests. • Notify your doctor if you experience symptoms such as infection, leg pain or swelling, chest pain, difficulty breathing, or severe stomach pain with fever, nausea, and vomiting.

Things you should not do: • Do not discontinue or alter the dosage of Rinvoq unless instructed by your doctor. • Refrain from sharing your medication with others, even if they have a similar condition.

Driving or using machines: • Rinvoq is unlikely to impair your ability to drive or operate machinery.

Drinking alcohol: • There is no available information regarding the interaction of Rinvoq with alcohol.

Looking after your medicine: • Store Rinvoq in a cool, dry place below 30°C, away from moisture, heat, and sunlight. • Keep the tablets in their original packaging until ready to use.

Rinvoq Prices

The price for Rinvoq oral tablet, extended release 15 mg, is approximately $6,782 for a supply of 30 tablets, varying depending on the pharmacy. It's important to note that quoted prices are for cash-paying customers and may not be applicable with insurance plans.